I'd like to do something with zombies, because I've always wanted to do something like that, and I've both read about them in philosophy courses and seen them in movies. They are a pretty hyper modern concept in lots of ways. I'm not sure exactly what to do with the idea, because it's been explored pretty well, but I think it could in some form try to be from the perspective of a zombie. This would make our protagonist either a regular human trapped in a zombie body who cannot control what he does (like a man in the depths of an ether binge, but with an overwhelming urge to dine on brains), or a somewhat child like, hyper violent monster who's morality is over run by a need to feed his addiction (like Ronald Reagan's conception of a crack addict). I prefer the first because it allows more freedom.
thoughts on how to do it:
1. Sonic mash-up: This would fit better with the latter idea. It would in theory try to mirror the perceptions of the zombie as he wanders around looking for chains to snatch and brains to eat. It would also probably be a lot of work and so is a secondary option at the moment.
2. Graphic Novel: Would need help, although I think it would probably still have to be cobbled together from photographs or pre existing pictures. this could also manifest itself as a collage comic, with little bits cut from other stuff. I think this would lead the tale to take a more comic turn, and who doesn't love zombie jokes?
3. Video Mash-up: This would also be neat to do with someone else as it is so time intensive, but since there is so much zombie material out there on video, it makes natural sense to use that source material. There is unfortunately not much non-fiction material out there, so the oral history is out. This is the next best thing. Again I think this would lead to many more comic moments.